Hamilton Regional Cancer Centre - August 2004


Hamilton Regional Cancer Centre
last updated August 2004

Open Trial Description

OV-16

Chemo
(Active)
Adjuvant 1st line Ovarian

Phase III study of Cisplatin + Topotecan x 4 PLUS Carbo + Taxol x 4 Versus Carbo + Taxol x 8

PFIZER

Targeted Therapy
(Hold)
Recurrent or persistent small volume ovarian

Phase II study of CP547, 632, an oral tyrosine kinase inhibitor of VEGFR-2

CINI

RCT of Immediate Treatment as follow up for biopsy proven CINI

PHL019

Chemo + targeted therapy (Active) Ovarian & Recurrent Primary Peritoneal

Phase II study of UCN01 + Topotecan in patients with advanced ovarian cancer

PHL020

Avastin + Cyclo (Active) Recurrent Ovarian & Primary Peritoneal

Phase II study of Bevacizumab + low dose oral Cyclophosphamide

IND. 154

Five solid tumours including ovarian (Active)

Phase I study of a clusterin antisense aligo-nucleatide (OGX-04) + low dose docetaxel

IND. 155

Alkylphospolipids (Hold) Sarcoma including Uterine

Phase II study of Perifosine (D-21266) PO daily
Recurrent Ovarian Cancer Treatment decision making in recurrent ovarian cancer
Recurrent Ovarian Cancer Bearing Witness

EN5

Radiation (Active) Adjuvant Endometrium

Phase III trial of pelvic rads versus observation post TAH/BSO-Stage 1 or 2A intermediate risk endometrial cancer

IND.160

Targeted Therapy (Active) Recurrent Endometrium

Phase II study of CC1-799 (Rapamycin) IV day 1, 8, 15, & 22 of 28 day cycles, a PTEN inhibitor

PMH – PIE

Chemo (Active) Advanced Cervical

Phase II study of Cisplatin, Irinotecan and Epirubicin in unresectable, locally advanced/metastatic cervical carcinoma

GT – 1

Chemo (Active) Low Risk GTN

Phase III study of Methotrexate versus Dactinomycin as primary management of low risk gestational trophoblastic neoplasm (GTN)